diff --git a/vmm/src/device_manager.rs b/vmm/src/device_manager.rs
index 776da603b..992436d60 100644
--- a/vmm/src/device_manager.rs
+++ b/vmm/src/device_manager.rs
@@ -18,6 +18,8 @@ use crate::device_tree::{DeviceNode, DeviceTree};
 use crate::interrupt::kvm::KvmMsiInterruptManager as MsiInterruptManager;
 use crate::interrupt::LegacyUserspaceInterruptManager;
 use crate::memory_manager::{Error as MemoryManagerError, MemoryManager};
+#[cfg(feature = "acpi")]
+use crate::vm::NumaNodes;
 #[cfg(feature = "pci_support")]
 use crate::PciDeviceInfo;
 use crate::{device_node, DEVICE_MANAGER_SNAPSHOT_ID};
@@ -805,9 +807,14 @@ pub struct DeviceManager {
 
     // seccomp action
     seccomp_action: SeccompAction,
+
+    // List of guest NUMA nodes.
+    #[cfg(feature = "acpi")]
+    numa_nodes: NumaNodes,
 }
 
 impl DeviceManager {
+    #[allow(clippy::too_many_arguments)]
     pub fn new(
         vm: Arc<dyn hypervisor::Vm>,
         config: Arc<Mutex<VmConfig>>,
@@ -816,6 +823,7 @@ impl DeviceManager {
         #[cfg_attr(target_arch = "aarch64", allow(unused_variables))] reset_evt: &EventFd,
         vmm_path: PathBuf,
         seccomp_action: SeccompAction,
+        #[cfg(feature = "acpi")] numa_nodes: NumaNodes,
     ) -> DeviceManagerResult<Arc<Mutex<Self>>> {
         let device_tree = Arc::new(Mutex::new(DeviceTree::new()));
 
@@ -878,6 +886,8 @@ impl DeviceManager {
             #[cfg(target_arch = "aarch64")]
             id_to_dev_info: HashMap::new(),
             seccomp_action,
+            #[cfg(feature = "acpi")]
+            numa_nodes,
         };
 
         #[cfg(feature = "acpi")]
@@ -2419,13 +2429,19 @@ impl DeviceManager {
 
         let mm = self.memory_manager.clone();
         let mm = mm.lock().unwrap();
-        for (_, memory_zone) in mm.memory_zones().iter() {
+        for (_memory_zone_id, memory_zone) in mm.memory_zones().iter() {
             if let (Some(region), Some(resize)) = (
                 memory_zone.virtio_mem_region(),
                 memory_zone.virtio_mem_resize(),
             ) {
                 let id = self.next_device_name(MEM_DEVICE_NAME_PREFIX)?;
 
+                #[cfg(not(feature = "acpi"))]
+                let node_id: Option<u16> = None;
+                #[cfg(feature = "acpi")]
+                let node_id = numa_node_id_from_memory_zone_id(&self.numa_nodes, _memory_zone_id)
+                    .map(|i| i as u16);
+
                 let virtio_mem_device = Arc::new(Mutex::new(
                     virtio_devices::Mem::new(
                         id.clone(),
@@ -2434,7 +2450,7 @@ impl DeviceManager {
                             .try_clone()
                             .map_err(DeviceManagerError::TryCloneVirtioMemResize)?,
                         self.seccomp_action.clone(),
-                        None,
+                        node_id,
                     )
                     .map_err(DeviceManagerError::CreateVirtioMem)?,
                 ));
@@ -3356,6 +3372,20 @@ impl DeviceManager {
     }
 }
 
+#[cfg(feature = "acpi")]
+fn numa_node_id_from_memory_zone_id(numa_nodes: &NumaNodes, memory_zone_id: &str) -> Option<u32> {
+    for (numa_node_id, numa_node) in numa_nodes.iter() {
+        if numa_node
+            .memory_zones()
+            .contains(&memory_zone_id.to_owned())
+        {
+            return Some(*numa_node_id);
+        }
+    }
+
+    None
+}
+
 #[cfg(feature = "acpi")]
 struct PciDevSlot {
     device_id: u8,
diff --git a/vmm/src/vm.rs b/vmm/src/vm.rs
index 6a02097af..122dbcacd 100644
--- a/vmm/src/vm.rs
+++ b/vmm/src/vm.rs
@@ -212,11 +212,12 @@ pub enum Error {
 }
 pub type Result<T> = result::Result<T, Error>;
 
-#[derive(Clone)]
+#[derive(Clone, Default)]
 pub struct NumaNode {
     memory_regions: Vec<Arc<GuestRegionMmap>>,
     cpus: Vec<u8>,
     distances: BTreeMap<u32, u8>,
+    memory_zones: Vec<String>,
 }
 
 impl NumaNode {
@@ -231,6 +232,10 @@ impl NumaNode {
     pub fn distances(&self) -> &BTreeMap<u32, u8> {
         &self.distances
     }
+
+    pub fn memory_zones(&self) -> &Vec<String> {
+        &self.memory_zones
+    }
 }
 
 pub type NumaNodes = BTreeMap<u32, NumaNode>;
@@ -317,6 +322,11 @@ impl Vm {
             .validate()
             .map_err(Error::ConfigValidation)?;
 
+        // Create NUMA nodes based on NumaConfig.
+        #[cfg(feature = "acpi")]
+        let numa_nodes =
+            Self::create_numa_nodes(config.lock().unwrap().numa.clone(), &memory_manager)?;
+
         let device_manager = DeviceManager::new(
             vm.clone(),
             config.clone(),
@@ -325,6 +335,8 @@ impl Vm {
             &reset_evt,
             vmm_path,
             seccomp_action.clone(),
+            #[cfg(feature = "acpi")]
+            numa_nodes.clone(),
         )
         .map_err(Error::DeviceManager)?;
 
@@ -352,11 +364,6 @@ impl Vm {
             .transpose()
             .map_err(Error::InitramfsFile)?;
 
-        // Create NUMA nodes based on NumaConfig.
-        #[cfg(feature = "acpi")]
-        let numa_nodes =
-            Self::create_numa_nodes(config.lock().unwrap().numa.clone(), &memory_manager)?;
-
         Ok(Vm {
             kernel,
             initramfs,
@@ -395,16 +402,13 @@ impl Vm {
                     return Err(Error::InvalidNumaConfig);
                 }
 
-                let mut node = NumaNode {
-                    memory_regions: Vec::new(),
-                    cpus: Vec::new(),
-                    distances: BTreeMap::new(),
-                };
+                let mut node = NumaNode::default();
 
                 if let Some(memory_zones) = &config.memory_zones {
                     for memory_zone in memory_zones.iter() {
                         if let Some(mm_zone) = mm_zones.get(memory_zone) {
                             node.memory_regions.extend(mm_zone.regions().clone());
+                            node.memory_zones.push(memory_zone.clone());
                         } else {
                             error!("Unknown memory zone '{}'", memory_zone);
                             return Err(Error::InvalidNumaConfig);